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Potassium oxonate induced hyperuricemia

Web5 Aug 2024 · Potassium oxonate induced acute HUA in tree shrews at lower doses compared with other animal models. Potassium oxonate-treated tree shrews may be a … Hyperuricemia is a metabolic disorder characterized by an excessively increased serum urate concentration, which may occur due to overproduction and/or insufficient intestinal excretion and/or urate underexcretion … See more The datasets analyzed in this article are publicly available. The RNA-seq data presented in the study are deposited in the public repository with GEO accession number GSE186871 or SRA accession number SRP343909. … See more In recent years, the prevalence of hyperuricemia has increased, and more and more young people are suffering from this disease (Yong et al., 2024). Febuxostat is more … See more

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http://www.globalauthorid.com/WebPortal/ArticleView?wd=7A280E01FD323750CF4EEB1C69E98B8F57771E2A7385B285 Web8 Apr 2024 · Renal herb formula (RHF) inhibited apoptosis in the kidney of mice with potassium oxonate-induced hyperuricemic nephropathy, as indicated by western blot … mixed to improper fractions worksheet pdf https://rejuvenasia.com

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Web12 Sep 2024 · Cellular cytoplasmic xanthine oxidase (XO)–mediated uric acid synthesis and extracellular excess uric acid exposure are both causes of cardiomyocytic injury under the … Web8 Jan 2024 · Potassium oxonate-induced hyperuricemic mice are appropriate experimental models for investigating the mechanism underlying hyperuricemia and for developing therapeutic agents. Allopurinol (AP) is an anti-hyperuricemic agent that acts by reducing XOD activity and serum UA levels. Web10 Dec 2024 · Study Design and Methods: Potassium oxonate (PO) induced hyperuricemia rats model and adenine-PO induced hyperuricemia mice model were used to evaluate the effects of EL. Ultraperformance liquid chromatography was used to determine the levels of plasma or serum uric acid and creatinine. mixed tomato chutney recipe

Insoluble Fiber in Barley Leaf Attenuates Hyperuricemic …

Category:Antihyperuricemic Effect of Dendropanax morbifera Leaf Extract …

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Potassium oxonate induced hyperuricemia

The Time-Feature of Uric Acid Excretion in Hyperuricemia Mice …

WebPotassium oxonate and allopurinol were purchased from Sigma-Aldrich Co., USA. Mice model of hyperuricemia and drug administration Different groups of mice, 8 animals per group, were used for drug treatment. Drugs were dissolved in 0.9% physi-ological saline. All doses were expressed as milligrams per kilogram body weight of the respective drugs ... http://www.globalauthorid.com/WebPortal/ArticleView?wd=FA07B4B65EA61D197522938978703073A94E995E1113ABCECF9E0725C64BCE30

Potassium oxonate induced hyperuricemia

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Web13 Aug 2024 · Hyperuricemia is the primary cause of gouty arthritis and other metabolic disorders. Eggshell membrane (EM) is an effective and safe supplement for curing pain and stiffness connected with osteoarthritis. However, the effect of EM on hyperuricemia is unclear. This study determines the effects of EM on potassium oxonate-injected … http://www.zhbybio.com/newsinfoen/6580.html?page=36

Web22 Nov 2024 · Hyperuricemia was induced by oral administration of potassium oxonate (PO) and hypoxanthine to mice for 7 days. The biochemical index results showed that treatments with low, medium, and high doses of IRh (50, 100, and 150 mg kg −1) significantly reduced serum UA levels and inhibited XOD activity in serum and in the liver.

Web23 Apr 2024 · This work aimed to investigate the effect of fucoidan (FPS) on urate transporters induced by uric acid (UA). The results showed that UA stimulated the expression of glucose transporter 9 (GLUT9) and urate transporter 1 (URAT1) in HK-2 cells, and FPS could reverse the effect. Moreover, UA could activate NF-κB, JNK and PI3K/Akt … WebMethods: Hyperuricemia was induced by potassium oxonate in male rats. AFPR was orally administered to hyperuricemic rats for 12 consecutive weeks. Serum, liver and kidney …

WebThe results indicated that SSO treatment prominently inhibited the increase of serum uric acid (UA), creatinine (CRE), and urea nitrogen (BUN) levels and hepatic xanthine oxidase …

Web5 Dec 2024 · Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway … ingress 403Web1 Aug 2024 · Potassium oxonate 1. Introduction Hyperuricemia is a common metabolic disease caused by increased uric acid (UA) synthesis and/or impaired UA excretion, which … ingress 404 page not foundWeb3 Aug 2024 · Hyperuricemia was associated with the overproduction or inadequate excretion of uric acid, while its association with gut microbiota has emerged although few studies were focused on it. Previously, we have reported a flavonoid extract from saffron floral bio-residues lowered uric acid in potassium oxonate-induced hyperuricemic mice. mixed to improper fraction worksheetWeb22 Jul 2024 · A hyperuricemia mouse model was established by potassium oxonate (PO) and adenine for 21 days. Ultra Performance Liquid Chromatography was used to … ingress 405WebSummary Xanthine oxidase (XO) plays an important role in the regulation of uric acid and prevents it from being overproduced as in hyperuricemia disease. The combined effects … ingress 404Web4 Sep 2024 · This study found that lemon water soluble extract (LET) can reduce uric acid levels in mice with potassium oxonate induced hyperuricemia. Histopathological analysis suggested that LET caused little damage to the kidneys of mice. It affected mABCG2 and mGLUT9 mRNA expression only in hyperuricemic mice, but not in healthy mice. ingress 443Web【Animal Modeling】-High-fat and high-purine diet combined with potassium oxonate induces glucose and lipid metabolism disorder and its complications in quail. To establish a practical animal model of chronic metabolic diseases, and to explore the correlation between hyperuricemia and glucose and lipid metabolism, as well as its pathological ... ingress 443 https