Lamp5 marker
Tīmeklis2024. gada 12. marts · Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions … TīmeklisLAMP5 is part of cluster 10 Brain - Neuronal signaling with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and …
Lamp5 marker
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Tīmeklis2024. gada 30. okt. · Notably, we identified layer 5 excitatory neurons without including a specific marker by combining the expression of the pan-excitatory marker Tbr1 and noting the absence of layer-specific... Tīmeklis2016. gada 2. dec. · In leukemia cells, using immunofluorescent confocal microscopy we detected LAMP5 in the perinuclear zones where it co-localized with ERGIC-53, a marker of the ERGIC compartment.
TīmeklisRetrieve cell markers of particular cell types in any tissues of interest in human and mouse. Obtain prevalence of cell markers in each cell type through a vivid statistical … Tīmeklis2016. gada 7. jūn. · LAMP5 is member of the LAMP family of membrane proteins. In contrast to the canonical members of this protein family, LAMP1 and LAMP2, which show widespread expression in many tissues, LAMP 5 is brain specific in mice. In C. elegans, the LAMP5 ortholog UNC-46 has been suggested to act a trafficking …
Tīmeklis2024. gada 1. maijs · Functional studies showed that LAMP5 is a novel autophagic suppressor and protects MLL fusion proteins from autophagic degradation. … Tīmeklis2024. gada 30. sept. · d, Scaled, normalized expression of select gene markers that distinguish the three main LAMP5 + types in marmoset. Extended Data Fig. 9 …
Tīmeklis2024. gada 1. apr. · LAMP-5 is an essential inflammatory-signaling regulator and novel immunotherapy target for mixed lineage leukemia-rearranged acute leukemia LAMP …
Tīmeklis2016. gada 2. dec. · We first confirmed LAMP5 expression in human leukemia cell lines by immunoblot and RT-qPCR assays. We readily detected LAMP5 mRNA and … f45 taylors lakesTīmeklis2024. gada 21. aug. · Marker genes for stringent clusters defined by four binary markers are provided in Supplementary Table 2. On average, neuronal nuclei were … f4999nt1zTīmeklis2024. gada 3. jūl. · LAMP5 limits neuronal hyperexcitation. a Latency to develop more severe seizures (left) and ranking of mean seizure severity score (right) reached within 10 min after intraperitoneal administration of 50 mg/kg pentylenetetrazole (PTZ) in 59 collaborative cross (CC; black) and 4 inbred strains (red). f47z-9b659-aTīmeklis2024. gada 11. dec. · The top 10 up-regulated genes found as survival markers of poor prognosis (i.e. low survival) were: DCBLD2, PTPN14, LAMP5, TM4SF1, NPR3, LEMD1, LCA5, CSGALNACT2, SLC2A3 and GADD45B. hindi ka paperTīmeklis2024. gada 1. apr. · LAMP5, a lysosomal associated membrane protein, is expressed highly and specifically in MLL-r leukemia. We found that LAMP5 is a direct target of the oncogenic MLL-fusion protein. LAMP5 depletion significantly inhibited leukemia cell growth in vitro and in vivo. Functional studies showed that LAMP-5 is a novel … hindi ka paper 2023 mp boardTīmeklisLysosome-associated membrane protein 5 (LAMP5), also known as BAD-LAMP, UNC-43, and C20orf103, is a new member of LAMP family. It is a transmembrane glycosylated protein localized in the ER-Golgi intermediate compartment (ERGIC). LAMP5 shares sequence and structural homology with the canonical LAMP1 … hindi ka paper 2022 kaTīmeklis2024. gada 2. janv. · We identified markers that distinguish L1 neurons and found that the layer contains four populations of GABAergic interneurons, each with unique molecular profiles, morphologies, and electrophysiological properties. ... 2024), which outlines four Lamp5 clusters (Egln3 and Pax6 subcategories) putatively spanning … hindi ka paper 9th class